Difference between revisions of "Ggt"

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|style="background:#ABCDEF;" align="center"|'''Function''' || degradation of poly-glutamate capsules  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || degradation of poly-glutamate capsules  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU18410 ggt]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18410 ggt]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 64 kDa, 5.453   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 64 kDa, 5.453   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yoeD]]'', ''[[yofA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yoeD]]'', ''[[yofA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13724&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU18410 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU18410 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU18410 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ggt_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ggt_context.gif]]

Revision as of 12:58, 13 May 2013

  • Description: gamma-glutamyltransferase

Gene name ggt
Synonyms pac
Essential no
Product gamma-glutamyltransferase
Function degradation of poly-glutamate capsules
Gene expression levels in SubtiExpress: ggt
MW, pI 64 kDa, 5.453
Gene length, protein length 1761 bp, 587 aa
Immediate neighbours yoeD, yofA
Sequences Protein DNA Advanced_DNA
Genetic context
Ggt context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Ggt expression.png















Categories containing this gene/protein

capsule biosynthesis and degradation

This gene is a member of the following regulons

Efp-dependent proteins

The gene

Basic information

  • Locus tag: BSU18410

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
    • strongly induced in response to glucose starvation in M9 medium PubMed
  • Regulatory mechanism:
  • Additional information:
    • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed