Difference between revisions of "NrnB"

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|style="background:#ABCDEF;" align="center"|'''Function''' || degradation of RNA oligonucleotides
 
|style="background:#ABCDEF;" align="center"|'''Function''' || degradation of RNA oligonucleotides
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU18200 nrnB]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18200 nrnB]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 5.026   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 5.026   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yngC]]'', ''[[yngE]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yngC]]'', ''[[yngE]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13703&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU18200 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU18200 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU18200 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yngD_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yngD_context.gif]]

Revision as of 12:57, 13 May 2013

  • Description: oligoribonuclease (nano-RNase)

Gene name nrnB
Synonyms yngD
Essential no
Product nano-RNase B
Function degradation of RNA oligonucleotides
Gene expression levels in SubtiExpress: nrnB
MW, pI 46 kDa, 5.026
Gene length, protein length 1197 bp, 399 aa
Immediate neighbours yngC, yngE
Sequences Protein DNA Advanced_DNA
Genetic context
YngD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NrnB expression.png
























Categories containing this gene/protein

Rnases

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU18200

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: degradation of RNA oligonucleotides PubMed
  • Protein family: DHH/DHHA1 protein family of phosphoesterases PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ming Fang, Wencke-Maria Zeisberg, Ciaran Condon, Vasily Ogryzko, Antoine Danchin, Undine Mechold
Degradation of nanoRNA is performed by multiple redundant RNases in Bacillus subtilis.
Nucleic Acids Res: 2009, 37(15);5114-25
[PubMed:19553197] [WorldCat.org] [DOI] (I p)