Difference between revisions of "MhqP"

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|style="background:#ABCDEF;" align="center"|'''Function''' || may be involved in protection against methyl-hydroquinone
 
|style="background:#ABCDEF;" align="center"|'''Function''' || may be involved in protection against methyl-hydroquinone
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU05500 mhqP]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU05500 mhqP]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 13 kDa, 8.62   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 13 kDa, 8.62   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mhqO]]'', ''[[ydfQ]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mhqO]]'', ''[[ydfQ]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12357&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU05500 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU05500 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU05500 Advanced_DNA]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ydfP_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ydfP_context.gif]]

Revision as of 12:13, 13 May 2013

  • Description: may be involved in protection against methyl-hydroquinone

Gene name mhqP
Synonyms ydfP
Essential no
Product unknown
Function may be involved in protection against methyl-hydroquinone
Gene expression levels in SubtiExpress: mhqP
MW, pI 13 kDa, 8.62
Gene length, protein length 387 bp, 129 aa
Immediate neighbours mhqO, ydfQ
Sequences Protein DNA Advanced_DNA
Genetic context
YdfP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MhqP expression.png
























Categories containing this gene/protein

general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

This gene is a member of the following regulons

MhqR regulon, SigB regulon

The gene

Basic information

  • Locus tag: BSU05500

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced by catechol and 2-methylhydroquinone (MhqR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefanie Töwe, Montira Leelakriangsak, Kazuo Kobayashi, Nguyen Van Duy, Michael Hecker, Peter Zuber, Haike Antelmann
The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis.
Mol Microbiol: 2007, 66(1);40-54
[PubMed:17725564] [WorldCat.org] [DOI] (P p)

Van Duy Nguyen, Carmen Wolf, Ulrike Mäder, Michael Lalk, Peter Langer, Ulrike Lindequist, Michael Hecker, Haike Antelmann
Transcriptome and proteome analyses in response to 2-methylhydroquinone and 6-brom-2-vinyl-chroman-4-on reveal different degradation systems involved in the catabolism of aromatic compounds in Bacillus subtilis.
Proteomics: 2007, 7(9);1391-408
[PubMed:17407181] [WorldCat.org] [DOI] (P p)

C W Price, P Fawcett, H Cérémonie, N Su, C K Murphy, P Youngman
Genome-wide analysis of the general stress response in Bacillus subtilis.
Mol Microbiol: 2001, 41(4);757-74
[PubMed:11532142] [WorldCat.org] [DOI] (P p)