YhaR

• Description: similar to enoyl CoA hydratase
  
  

Gene name	yhaR
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yhaR
MW, pI	27 kDa, 6.355
Gene length, protein length	765 bp, 255 aa
Immediate neighbours	yhaS, yhzD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

membrane proteins, poorly characterized/ putative enzymes, sporulation proteins

This gene is a member of the following regulons

CcpA regulon

The gene

Basic information

• Locus tag: BSU09880

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O07533

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yhaR PubMed

• Sigma factor:

• Regulation: repressed by glucose (17-fold) (CcpA) PubMed

• Regulatory mechanism: CcpA: transcription repression

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135] [WorldCat.org] [DOI] (P p)