Difference between revisions of "YrvM"
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| − | * '''Description:''' | + | * '''Description:''' similar to E. coli enzyme that catalyzes ATP-dependent dehydration of N6-threonylcarbamoyladenosine (t6A) to form cyclic N6-threonylcarbamoyladenosine (ct6A) <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || N6-threonylcarbamoyladenosine cyclase |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU27540 yrvM] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU27540 yrvM] | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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<br/><br/> | <br/><br/> | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[ | + | {{SubtiWiki category|[[translation]]}} |
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** catalyzes ATP-dependent dehydration of N6-threonylcarbamoyladenosine (t6A) to form cyclic N6-threonylcarbamoyladenosine (ct6A) (ct6A recognizes the first adenine base of ANN codon at the ribosomal A site) {{PubMed|23242255}} | ||
* '''Protein family:''' | * '''Protein family:''' | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| − | * '''Localization:''' | + | * '''[[Localization]]:''' |
=== Database entries === | === Database entries === | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yrvM_2813643_2814407_-1 yrvM] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yrvM_2813643_2814407_-1 yrvM] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
| − | + | <pubmed> 23242255 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 14:15, 28 January 2013
- Description: similar to E. coli enzyme that catalyzes ATP-dependent dehydration of N6-threonylcarbamoyladenosine (t6A) to form cyclic N6-threonylcarbamoyladenosine (ct6A)
| Gene name | yrvM |
| Synonyms | |
| Essential | no |
| Product | N6-threonylcarbamoyladenosine cyclase |
| Function | tRNA modification |
| Gene expression levels in SubtiExpress: yrvM | |
| MW, pI | 28 kDa, 8.187 |
| Gene length, protein length | 762 bp, 254 aa |
| Immediate neighbours | yrvN, bsrA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27540
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- catalyzes ATP-dependent dehydration of N6-threonylcarbamoyladenosine (t6A) to form cyclic N6-threonylcarbamoyladenosine (ct6A) (ct6A recognizes the first adenine base of ANN codon at the ribosomal A site) PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O32037
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kenjyo Miyauchi, Satoshi Kimura, Tsutomu Suzuki
A cyclic form of N6-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification.
Nat Chem Biol: 2013, 9(2);105-11
[PubMed:23242255]
[WorldCat.org]
[DOI]
(I p)
