Difference between revisions of "SpsI"
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| − | * '''Description:''' spore coat polysaccharide synthesis <br/><br/> | + | * '''Description:''' glucose-1-phosphate thymidylyltransferase, spore coat polysaccharide synthesis <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || glucose-1-phosphate thymidylyltransferase |
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || spore coat polysaccharide synthesis | + | |style="background:#ABCDEF;" align="center"|'''Function''' || rhamnose biosynthesis, spore coat polysaccharide synthesis |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU37840 spsI] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU37840 spsI] | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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<br/><br/> | <br/><br/> | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[miscellaneous metabolic pathways]]}}, | ||
{{SubtiWiki category|[[sporulation proteins]]}} | {{SubtiWiki category|[[sporulation proteins]]}} | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** alpha-D-glucose-1-phosphate + dTTP --> dTDP-glucose {{PubMed|22960854}} | ||
* '''Protein family:''' glucose-1-phosphate thymidylyltransferase family (according to Swiss-Prot) | * '''Protein family:''' glucose-1-phosphate thymidylyltransferase family (according to Swiss-Prot) | ||
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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU37840] | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU37840] | ||
| − | * '''E.C. number:''' | + | * '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.7.24 2.7.7.24] |
=== Additional information=== | === Additional information=== | ||
Revision as of 16:03, 18 September 2012
- Description: glucose-1-phosphate thymidylyltransferase, spore coat polysaccharide synthesis
| Gene name | spsI |
| Synonyms | ipa-71d |
| Essential | no |
| Product | glucose-1-phosphate thymidylyltransferase |
| Function | rhamnose biosynthesis, spore coat polysaccharide synthesis |
| Gene expression levels in SubtiExpress: spsI | |
| MW, pI | 27 kDa, 5.385 |
| Gene length, protein length | 738 bp, 246 aa |
| Immediate neighbours | spsJ, spsG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU37840
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
- A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- alpha-D-glucose-1-phosphate + dTTP --> dTDP-glucose PubMed
- Protein family: glucose-1-phosphate thymidylyltransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P39629
- KEGG entry: [3]
- E.C. number: 2.7.7.24
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
- the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
