Difference between revisions of "SigW"

From SubtiWiki
Jump to: navigation, search
(References)
Line 39: Line 39:
 
{{SubtiWiki regulon|[[AbrB regulon]]}},
 
{{SubtiWiki regulon|[[AbrB regulon]]}},
 
{{SubtiWiki regulon|[[SigW regulon]]}}
 
{{SubtiWiki regulon|[[SigW regulon]]}}
 
+
=The [[SigW regulon]]=
 
=The gene=
 
=The gene=
  
Line 68: Line 68:
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
 
=== Genes controlled by SigW ===
 
 
''[[abh]]'', ''[[pbpE]]-[[racX]]'',''[[xpaC]]-[[yaaN]]'', ''[[yteI]], [[yuaG]], [[yknX| yknXYZ]], [[ydjP]], [[yfhM]]''
 
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
Line 139: Line 135:
 
=References=
 
=References=
 
'''Additional publications:''' {{PubMed|20817771}}
 
'''Additional publications:''' {{PubMed|20817771}}
 +
==The [[SigW regulon]]==
 +
<pubmed>9683469,16629676,17675383,11866510,9987136,10960106, 11454200,14563871,12076816, 19820159 </pubmed>
 
==Other original publications==
 
==Other original publications==
<pubmed>9683469,11222589,16629676,14993308,16816000,17675383,11866510,17338440,9987136,12207695, 10960106, 11454200,14563871,12076816, 19820159 </pubmed>
+
<pubmed>11222589,14993308,16816000,17338440,12207695, 11454200,14563871,12076816, 19820159 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 20:18, 10 December 2010

Gene name sigW
Synonyms ybbL
Essential no
Product RNA polymerase ECF-type sigma factor SigW
Function resistance against SdpC
that functions in detoxification and/or
production of antimicrobial compounds
MW, pI 21 kDa, 8.614
Gene length, protein length 561 bp, 187 aa
Immediate neighbours trnSL-Gln2, ybbM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SigW context.gif
This image was kindly provided by SubtiList





Categories containing this gene/protein

transcription, sigma factors and their control, cell envelope stress proteins (controlled by SigM, W, X, Y)

This gene is a member of the following regulons

AbrB regulon, SigW regulon

The SigW regulon

The gene

Basic information

  • Locus tag: BSU01730

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ECF subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: RsiW acts as antagonist of SigW (anti-SigW)
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced under conditions of alkali shock or in the presence of the toxin SdpC (SigW) PubMed
    • repressed during logrithmic growth (AbrB) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Thomas Wiegert, University of Bayreuth, Germany Homepage

Your additional remarks

References

Additional publications: PubMed

The SigW regulon

Other original publications