Difference between revisions of "LytC"

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= Categories containing this gene/protein =
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{{SubtiWiki category|[[cell wall degradation/ turnover]]}},
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{{SubtiWiki category|[[motility and chemotaxis]]}}
 
=The protein=
 
=The protein=
  

Revision as of 17:46, 30 November 2010

  • Description: N-acetylmuramoyl-L-alanine amidase, required for flagellar function PubMed

Gene name lytC
Synonyms cwlB
Essential no
Product N-acetylmuramoyl-L-alanine amidase

(EC 3.5.1.28)

Function major autolysin, cell separation, wall turnover

lysis, motility and general cell lysis induced by sodium azide

MW, pI 52 kDa, 10.108
Gene length, protein length 1488 bp, 496 aa
Immediate neighbours tuaA, lytB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LytC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU35620

Phenotypes of a mutant

impaired in motility, the phenotype is suppressed by mutations in lonA or smiA PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

cell wall degradation/ turnover, motility and chemotaxis

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)
  • Protein family: N-acetylmuramoyl-L-alanine amidase 3 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: secreted (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References