Difference between revisions of "Biofilm formation"

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Biofilms are the result of the multicellular lifestyle of ''B. subtilis''. They are characterized by the formation of a matrix polysaccharide and an amyloid-like protein, [[TasA]].
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==[http://subtiwiki.uni-goettingen.de/pathways/biofilm.html Biofilm formation in ''Subti''Pathways]==
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==Labs working on biofilm formation==
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* [[Daniel Kearns]]
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* [[Oscar Kuipers]]
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* [[Beth Lazazzera]]
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* [[Richard Losick]]
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* [[Nicola Stanley-Wall]]
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==Key genes and operons involved in biofilm  formation==
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* matrix polysaccharide synthesis:
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** ''[[epsA]]-[[epsB]]-[[epsC]]-[[epsD]]-[[epsE]]-[[epsF]]-[[epsG]]-[[epsH]]-[[epsI]]-[[epsJ]]-[[epsK]]-[[epsL]]-[[epsM]]-[[epsN]]-[[epsO]]''
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* amyloid protein synthesis
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** ''[[yqxM]]-[[sipW]]-[[tasA]]''
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* regulation
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** [[SlrR]]
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** [[SlrA]]
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** [[SinR]]
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** [[SinI]]
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** [[PtkA]]
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** [[TkmA]]
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** [[PtpZ]]
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** [[DegU]]
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** [[RacX]]
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* biofilm disassembly
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** [[YlmE]]
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* other proteins required for biofilm formation
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** [[SpeA]]
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** [[YmcA]]
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** [[YxaB]]
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==Key reviews==
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<pubmed>19054118 19054118 16787201 9891794 20890834  </pubmed>
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* additional reviews: {{PubMed|20735481}}

Revision as of 14:39, 11 November 2010

Biofilms are the result of the multicellular lifestyle of B. subtilis. They are characterized by the formation of a matrix polysaccharide and an amyloid-like protein, TasA.

Parent categories
Neighbouring categories
Related categories

none

Biofilm formation in SubtiPathways

Labs working on biofilm formation

Key genes and operons involved in biofilm formation

Key reviews

Roberto Kolter
Biofilms in lab and nature: a molecular geneticist's voyage to microbial ecology.
Int Microbiol: 2010, 13(1);1-7
[PubMed:20890834] [WorldCat.org] [DOI] (I p)

Daniel Lopez, Hera Vlamakis, Roberto Kolter
Generation of multiple cell types in Bacillus subtilis.
FEMS Microbiol Rev: 2009, 33(1);152-63
[PubMed:19054118] [WorldCat.org] [DOI] (P p)

Wolf-Rainer Abraham
Controlling biofilms of gram-positive pathogenic bacteria.
Curr Med Chem: 2006, 13(13);1509-24
[PubMed:16787201] [WorldCat.org] [DOI] (P p)

J A Shapiro
Thinking about bacterial populations as multicellular organisms.
Annu Rev Microbiol: 1998, 52;81-104
[PubMed:9891794] [WorldCat.org] [DOI] (P p)