Difference between revisions of "FadM"
Line 98: | Line 98: | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
+ | ** [[FadR]]: transcription repression {{PubMed|17189250}} | ||
** [[SdpR]]: transcription activation {{PubMed|12817086}} | ** [[SdpR]]: transcription activation {{PubMed|12817086}} | ||
Revision as of 19:24, 12 May 2010
- Description: fatty acid degradation, similar to proline dehydrogenase
Gene name | fadM |
Synonyms | yusM |
Essential | no |
Product | unknown |
Function | fatty acid degradation |
Metabolic function and regulation of this protein in SubtiPathways: Fatty acid degradation | |
MW, pI | 34 kDa, 9.377 |
Gene length, protein length | 906 bp, 302 aa |
Immediate neighbours | fadN, yusN |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU32850
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor (according to Swiss-Prot)
- Protein family: proline dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s): YcgM
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O32179
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250]
[WorldCat.org]
[DOI]
(P p)
José E González-Pastor, Errett C Hobbs, Richard Losick
Cannibalism by sporulating bacteria.
Science: 2003, 301(5632);510-3
[PubMed:12817086]
[WorldCat.org]
[DOI]
(I p)