Difference between revisions of "LiaR"

From SubtiWiki
Jump to: navigation, search
(Biological materials)
Line 1: Line 1:
* '''Description:''' two-component response regulator, regulation of the  liaI-liaH-liaG-liaF-liaS-liaR operon in response to bacitracin <br/><br/>
+
* '''Description:''' two-component response regulator, regulation of the  ''[[liaI]]-[[liaH]]-[[liaG]]-[[liaF]]-[[liaS]]-[[liaR]]'' operon in response to bacitracin <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 104: Line 104:
 
=Biological materials =
 
=Biological materials =
  
* '''Mutant:''' HB0933 (aphA3), available in the [[Thorsten Mascher]] lab
+
* '''Mutant:'''  
  
 
* '''Expression vector:'''
 
* '''Expression vector:'''
Line 120: Line 120:
 
[[John Helmann]], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
 
[[John Helmann]], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
  
[[Thorsten Mascher]], Karlsruhe Institute of Technology, Germany [http://microbial-stress.iab.kit.edu/ link]
 
  
 
=Your additional remarks=
 
=Your additional remarks=

Revision as of 21:40, 17 November 2009

  • Description: two-component response regulator, regulation of the liaI-liaH-liaG-liaF-liaS-liaR operon in response to bacitracin

Gene name liaR
Synonyms yvqC
Essential no
Product two-component response regulator
Function regulation of the liaI-liaH-liaG-liaF-liaS-liaR operon in response to bacitracin
MW, pI 22 kDa, 4.956
Gene length, protein length 633 bp, 211 aa
Immediate neighbours gerAC, liaS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvqC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU33080

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

liaS-liaR

  • Regulation: liaI: induced by bacitracin (LiaR)

liaS: constitutive

  • Regulatory mechanism: LiaR: transcription activation
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage


Your additional remarks

References