yxeN

168

putative S-(2-succino)cysteine [wiki|ABC transporter] (permease)

locus: BSU_39490

Molecular weight: 24.86 kDa

pI: 9.48

Protein length: 224 aa

Gene length: 675 bp

function: uptake and utilization of S-(2-succino)cysteine

product: putative S-(2-succino)cysteine [wiki|ABC transporter] (permease)

essential: no

synonyms: yxeN

List of homologs in different organisms, belongs to COG0765 (Galperin et al., 2021)

Gene

Coordinates: 4,058,791 → 4,059,465

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The protein

Protein family

• [wiki|Binding-protein-dependent transport system permease family] (according to UniProt)

[wiki|Domains]

• [wiki|ABC transmembrane type-1 domain] (aa 20-211) (according to UniProt)

Structure

• [PDB|4YMS] (amino acid transporter from Caldanaerobacter subterraneus, 39% identity) [pubmed|25848002]
• [AF|P54953]

Paralogous protein(s)

• [protein|350C97E4A4C60A6E2FF9610D50B4A49FB9F9B42D|tcyL], [protein|9400DF25487461E3738DDDC72BDDB1589281409D|tcyB], [protein|1872614A6F7DBF7231348AC3DAE4ED3295ACEB41|yckA]

[wiki|Localization]

• cell membrane (according to UniProt)

Biological materials

Mutant

• MGNA-B710 (yxeN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1709 NBRP B. subtilis, Japan]
• 1A950 ( ''yxeN''::''cat''), [Pubmed|15262924], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A950&Search=1A950 BGSC]
• BKE39490 (Δ[gene|FFD5F07480A0E5A74852C69C436EE289BA72FC7F|yxeN]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE39490 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCTGGTGAGTCACCGCC,  downstream forward: _UP4_TACCGGACTTAGAGGTGAAA
• BKK39490 (Δ[gene|FFD5F07480A0E5A74852C69C436EE289BA72FC7F|yxeN]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK39490 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCTGGTGAGTCACCGCC,  downstream forward: _UP4_TACCGGACTTAGAGGTGAAA

References

• 10746760,10092453,16513748,18763711,29626092,25848002