ywcH

ywcH
168

similar to monooxygenase

locus
BSU_38100
Molecular weight
36.40 kDa
pI
5.94
Protein length
Gene length
function
unknown
product
unknown
essential
no
synonyms
ywcH, ipa-44d

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2141 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,910,302  3,911,303
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The protein
Structure
[PDB|4US5] (from Streptomyces bottropensis, 39% identity) [pubmed|24554499]
[AF|P39606]
Paralogous protein(s)
[protein|A36E7D50E2EBD0F0109491FF2CAD2CA84372B2CF|yvbT], [protein|EDC3565D90D7059A4A4C66A13EB568420F6CECD4|cmoO], [protein|1432F56AD3D2B2BD82D8759CE4DC42C0D40C49C0|yceB]
Expression and Regulation
Operons
genes
[gene|5B95F7CFEFCB954FCBC11087F030A1D777F34B7A|nfrA]-[gene|A1DCFF8D225C87197104742E72A0D4F238BC30EB|ywcH]
description
[Pubmed|10913069]
regulation
repressed under conditions that trigger sporulation ([wiki|Spo0A]) [Pubmed|14651647]
induced by cell wall stress ([protein|2C6386E9A63F410558D168798D077DF91590F454|spx]) [pubmed|29271514]
regulatory mechanism
[protein|2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A]: repression, [Pubmed|14651647], in [regulon|protein:2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A regulon]
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [Pubmed|29271514,12642660,19575568], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|10913069], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|7024E4162A6D827069F882FDEACA696EBC05DD40|sigD]: sigma factor, [Pubmed|9535080], in [regulon|protein:7024E4162A6D827069F882FDEACA696EBC05DD40|sigD regulon]
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[gene|5B95F7CFEFCB954FCBC11087F030A1D777F34B7A|nfrA]→[gene|A1DCFF8D225C87197104742E72A0D4F238BC30EB|ywcH]

2024-03-26 00:07:44

Jstuelk

70

720c222b08abba1830cf73bc448bc404c885599c

AA9A68C6886357B0F73EF2C7A4E0AA662D15B3C3

Biological materials
Mutant
MGNA-B233 (ywcH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1232 NBRP B. subtilis, Japan]
BKE38100 ([gene|A1DCFF8D225C87197104742E72A0D4F238BC30EB|ywcH]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38100 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCCTACCACCTCATCCT,  downstream forward: _UP4_TGATCTTTAAAAAGCCCTGC
BKK38100 ([gene|A1DCFF8D225C87197104742E72A0D4F238BC30EB|ywcH]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38100 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCCTACCACCTCATCCT,  downstream forward: _UP4_TGATCTTTAAAAAGCCCTGC
References
10913069,9535080,14651647,24554499

A1DCFF8D225C87197104742E72A0D4F238BC30EB

Page visits: 3737

Time of last update: 2024-03-29 07:18:23

Author of last update: Melvin.boenninger