yvkC

168

flavonoid phosphate synthetase

locus: BSU_35190

Molecular weight: 94.25 kDa

pI: 4.62

Protein length: 831 aa

Gene length: 2496 bp

function: unknown

product: flavonoid phosphate synthetase

essential: no

synonyms: yvkC

List of homologs in different organisms, belongs to COG0574 (Galperin et al., 2021)

Gene

Coordinates: 3,615,793  3,618,288

Advertisement

The protein

Catalyzed reaction/ biological activity

• ATP-dependent phosphorylation of flavonoid to generate flavonoid monophosphates, AMP and orthophosphate [pubmed|36084586]

Protein family

• [wiki|PEP-utilizing enzyme family] (according to UniProt)

Structure

• [PDB|5FBU](rifampin phosphotransferase from Listeria monocytogenes, 34% identity) [pubmed|27103605]
• [AF|O34796]

Paralogous protein(s)

• [protein|BF0329D469211F579F5CF0CBB58A6D96DD8CB839|pps]

Expression and Regulation

Operons

• genes: [gene|7235F9D0048961BBD93FA6A4322018029A607435|yvkC]-[gene|672EAC84789910ADB2C2A449910BEECA39A9A2B1|yvkB]-[gene|F4028F82CCF1A0335D1ABF823645A36D9072F17F|yvkA]

  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A341 (yvkC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/341 NBRP B. subtilis, Japan]
• BKE35190 ([gene|7235F9D0048961BBD93FA6A4322018029A607435|yvkC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE35190 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATTTGAAACCCCTCTTT,  downstream forward: _UP4_TGATGCGTCCCCCTCTTTCT
• BKK35190 ([gene|7235F9D0048961BBD93FA6A4322018029A607435|yvkC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK35190 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATTTGAAACCCCTCTTT,  downstream forward: _UP4_TGATGCGTCCCCCTCTTTCT

Original Publications

• 36084586,27103605