ytoP

168

similar to glutamyl aminopeptidase

locus: BSU_29860

Molecular weight: 39.08 kDa

pI: 5.65

Protein length: 357 aa

Gene length: 1074 bp

function: unknown

product: putative glutamyl aminopeptidase

essential: no

synonyms: ytoP

List of homologs in different organisms, belongs to COG1363 (Galperin et al., 2021)

Gene

Coordinates: 3,055,247  3,056,320

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The protein

Protein family

• Peptidase M42 family (with [protein|D6F5F7C1C699C674FA7AC09A020E8E2F571E1AA9|ysdC] and [protein|EDD5ACB89661D3B6D77057863EF345EBF84F49B2|yhfE], according to UniProt)

Structure

• [PDB|3KL9] (PepA from Streptococcus pneumoniae, 44% identity) [pubmed|19914209]
• [AF|O34924]

Paralogous protein(s)

• [protein|D6F5F7C1C699C674FA7AC09A020E8E2F571E1AA9|ysdC]

Expression and Regulation

Operons

• genes: [gene|16585F4118F3D2732D6780D351B7AA5F6DDCCEB8|ytoP]

  description: [pubmed|22383849]

Biological materials

Mutant

• MGNA-A436 (ytoP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/436 NBRP B. subtilis, Japan]
• BKE29860 ([gene|16585F4118F3D2732D6780D351B7AA5F6DDCCEB8|ytoP]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29860 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTCCCCTCATTTCT,  downstream forward: _UP4_TAGGTTTCATAAAAGCTTGT
• BKK29860 ([gene|16585F4118F3D2732D6780D351B7AA5F6DDCCEB8|ytoP]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29860 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTCCCCTCATTTCT,  downstream forward: _UP4_TAGGTTTCATAAAAGCTTGT
• BP1240([gene|16585F4118F3D2732D6780D351B7AA5F6DDCCEB8|ytoP]::phleo trp+) available in [wiki|Jörg Stülke]'s & [wiki|Fabian Commichau]'s lab

References

Research papers

• 19914209