yqxK

168

similar to lesion-specific endonuclease EndoQ, binds to DNA lesions, may be involved in DNA repair

locus: BSU_23600

Molecular weight: 32.03 kDa

pI: 8.45

Protein length: 387 aa

Gene length: 1164 bp

function: unknown

product: unknown

essential: no

synonyms: yqxK, yqkH

List of homologs in different organisms, belongs to COG1379 (Galperin et al., 2021)

Gene

Coordinates: 2,457,349  2,458,512

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The protein

Catalyzed reaction/ biological activity

• binds to abasic DNA lesions [pubmed|37250769]

Structure

• [PDB|5ZB8] (from Pyrococcus furiosus, 34% identity)
• [AF|P38423]

Expression and Regulation

Operons

• genes: [gene|CF38BE04F04919BB304789E9B3FE489385E468E6|nudF]-[gene|9D05B104000EED08FB62D6F362FC5E9C2A5354D9|yqxK]

  description: [Pubmed|22383849]

Biological materials

Mutant

• BKE23600 ([gene|9D05B104000EED08FB62D6F362FC5E9C2A5354D9|yqxK]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE23600 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GTGCAAATCCGCGTAAATCT,  downstream forward: _UP4_AAAATTAAACCGTGAGCTAA
• BKK23600 ([gene|9D05B104000EED08FB62D6F362FC5E9C2A5354D9|yqxK]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK23600 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GTGCAAATCCGCGTAAATCT,  downstream forward: _UP4_AAAATTAAACCGTGAGCTAA

References

Research papers

• 29660024,37250769