yneI

168

two-component response regulator

locus: BSU_17940

Molecular weight: 13.40 kDa

pI: 6.95

Protein length: 120 aa

Gene length: 363 bp

function: unknown

product: two-component response regulator

essential: no

synonyms: yneI, yoxH, ccdB

List of homologs in different organisms, belongs to COG4753 (Galperin et al., 2021)

Gene

Coordinates: 1,924,030  1,924,392

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The protein

[wiki|Domains]

• [wiki|Response regulatory domain] (aa 3-118) (according to UniProt)

Structure

• [PDB|1TMY] ([protein|2F0495C7EAB81BDB1F3181677C555537BD2A972F|cheY] from ''Thermotoga maritima'', 57% identity)
• [AF|P45709]

Paralogous protein(s)

• [protein|2F0495C7EAB81BDB1F3181677C555537BD2A972F|cheY]

Expression and Regulation

Operons

• genes: [gene|27A25671205E9F6475A1EF00C72F9239AA2A767A|ccdA]-[gene|AE823A0A652509787EA032F122E59F3C3645385F|yneI]-[gene|D869177D5B1CE8B72AF89A18F03D8176ADA42664|yneJ]

  description: [Pubmed|9068642]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|10781554], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]

Biological materials

Mutant

• BKE17940 (''yneI''::''ermC'') (available at the [http://bgsc.org/ BGSC] and in [wiki|Jörg Stülke]'s lab) [pubmed|28189581]
• GP1866 (''yneI''::''ermC'') (available in [wiki|Jörg Stülke]'s lab)
• BKE17940 ([gene|AE823A0A652509787EA032F122E59F3C3645385F|yneI]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE17940 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATTCCCCTCCAACAATC,  downstream forward: _UP4_TAAAGTCATTTCTTTTCAAA
• BKK17940 ([gene|AE823A0A652509787EA032F122E59F3C3645385F|yneI]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK17940 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATTCCCCTCCAACAATC,  downstream forward: _UP4_TAAAGTCATTTCTTTTCAAA

References

• 9068642,10781554,10094672