ymxH

168

sporulation protein

locus: BSU_16720

Molecular weight: 9.63 kDa

pI: 5.44

Protein length: 85 aa

Gene length: 258 bp

function: unknown

product: sporulation protein

essential: no

ec: null

synonyms: ymxH

List of homologs in different organisms, belongs to COG1873 (Galperin et al., 2021)

Gene

Coordinates: 1,743,924  1,744,181

Phenotypes of a mutant

• a ''[gene|1D27C5E73571A737B80649BFCF517C5FF136DFFF|ylmC] [gene|AC541AB15B4A2BC345B471BD654299BAEC3E8635|ymxH]'' double mutant has a severe [wiki|sporulation] defect (1% [wiki|sporulation] as compared to the wild type or single mutants), the block is at stage III of [wiki|sporulation]  [Pubmed|23396918]

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The protein

Protein family

• YlmC/YmxH family (with [protein|1D27C5E73571A737B80649BFCF517C5FF136DFFF|ylmC], according to UniProt)

Structure

• [AF|Q04811]

Paralogous protein(s)

• [protein|1D27C5E73571A737B80649BFCF517C5FF136DFFF|ylmC]

Expression and Regulation

Operons

• genes: [gene|AC541AB15B4A2BC345B471BD654299BAEC3E8635|ymxH]

  description: [Pubmed|22383849,8098035]

  regulation

  • expressed early during [wiki|sporulation] in the mother cell ([protein|search|SigE]) [Pubmed|22383849,14523133]

  sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|22383849,14523133], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]

Biological materials

Mutant

• BKE16720 ([gene|AC541AB15B4A2BC345B471BD654299BAEC3E8635|ymxH]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE16720 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTCTGTCACCCCCTTGT,  downstream forward: _UP4_TAAATAGCCCAATTGACTGT
• BKK16720 ([gene|AC541AB15B4A2BC345B471BD654299BAEC3E8635|ymxH]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK16720 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTCTGTCACCCCCTTGT,  downstream forward: _UP4_TAAATAGCCCAATTGACTGT

References

• 8098035,23123912,22383849,14523133,35638784