yisX

168

binds to DNA lesions, may be involved in DNA damage repair

Locus: BSU_10890

Molecular weight: 23.58 kDa

Isoelectric point: 5.05

Protein length: 212 aa

Gene length: 639 bp

Function: unknown

Product: unknown

Essential: no

E.C.: null

Synonyms: yisX

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG1357 (Galperin et al., 2021)

Gene

Coordinates: 1,168,199  1,168,837

The protein

Catalyzed reaction/ biological activity

• binds to 8-oxoG and RNA base DNA lesions PubMed

Domains

• 3 Pentapeptide repeat domains (aa 63-102, aa 103-142, aa 143-182) (according to UniProt)

Structure

• 6FLS (PDB) (from Clostridium botulinum, corresponds to aa 28 ... 235, 24% identity) PubMed
• O06733 (AlphaFold)

Expression and Regulation

Operons

• Genes: yisX

  Description: PubMed

Biological materials

Mutant

• MGNA-B193 (yisX::erm), available at the NBRP B. subtilis, Japan
• BKE10890 (yisX::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGATGACATCCTTTGC,  downstream forward: _UP4_GGAGCTGTCATCGTATAACC
• BKK10890 (yisX::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGATGACATCCTTTGC,  downstream forward: _UP4_GGAGCTGTCATCGTATAACC

References

Research papers

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