ydcG

168

binds to DNA lesions, may be involved in DNA repair

locus: BSU_04760

Molecular weight: 16.46 kDa

pI: 9.61

Protein length: 146 aa

Gene length: 441 bp

function: unknown

product: unknown

essential: no

synonyms: ydcG

List of homologs in different organisms

Gene

Coordinates: 524,782  525,222

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The protein

Catalyzed reaction/ biological activity

• binds to RNA base DNA lesions [pubmed|37250769]

Protein family

• UPF0310 family (single member, according to UniProt)

Structure

• [AF|P96624]

Expression and Regulation

Operons

• genes: [gene|20D50DA11B864E6C719CC34BE27C7900893EA054|ydcF]-[gene|89AB146F447696EF1CBE219C9A2FB5CBB380F847|ydcG]-[gene|B7F5FA5C656D39970959BC857E93B78B1A063098|pamR]

  description: [pubmed|29240826,22383849]

  regulatory mechanism

  • [protein|B7F5FA5C656D39970959BC857E93B78B1A063098|pamR]: repression, [pubmed|29240826], in [regulon|protein:B7F5FA5C656D39970959BC857E93B78B1A063098|pamR regulon]

• genes: [gene|89AB146F447696EF1CBE219C9A2FB5CBB380F847|ydcG]-[gene|B7F5FA5C656D39970959BC857E93B78B1A063098|pamR]

  description: [pubmed|22383849]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [pubmed|22383849], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]

Biological materials

Mutant

• MGNA-C095 (ydcG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2093 NBRP B. subtilis, Japan]
• BKE04760 ([gene|89AB146F447696EF1CBE219C9A2FB5CBB380F847|ydcG]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04760 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_AACGCCGATCCAGTAATTTG,  downstream forward: _UP4_GCACAAGCGATGGGAGTTAA
• BKK04760 ([gene|89AB146F447696EF1CBE219C9A2FB5CBB380F847|ydcG]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04760 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_AACGCCGATCCAGTAATTTG,  downstream forward: _UP4_GCACAAGCGATGGGAGTTAA

References

Research papers

• 29240826,37250769