ydbD

168

general stress protein, similar to manganese-containing catalase

locus: BSU_04430

Molecular weight: 30.11 kDa

pI: 4.86

Protein length: 273 aa

Gene length: 822 bp

function: survival of ethanol stress

product: unknown

essential: no

synonyms: ydbD

List of homologs in different organisms, belongs to COG3546 (Galperin et al., 2021)

Gene

Coordinates: 495,740  496,561

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The protein

Catalyzed reaction/ biological activity

• 2 H₂O₂ --> O₂ + 2 H₂O (according to UniProt)

Protein family

• [wiki|catalase family] (according to UniProt)

Structure

• [PDB|1JKU] (from Lactobacillus plantarum, 51% identity) [pubmed|11587647]
• [AF|P80878]

Paralogous protein(s)

• [protein|59EC45E8731FE989152553A69ACEF6569E88F85C|yjqC], [protein|8F21A4C6228A772B38597991AF43E6B0708339BF|cotJC]

Expression and Regulation

Operons

• genes: [gene|7428E80AC67A659B8602AF887EA7DFFD4976B40C|dctB]-[gene|01CE4BBBEB0C0855201D396FB8036F72B64EA7DD|ydbD]

  description: [Pubmed|10708364]

  regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|15805528]

  sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]

• genes: [gene|01CE4BBBEB0C0855201D396FB8036F72B64EA7DD|ydbD]

  regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|15805528]

Biological materials

Mutant

• BKE04430 ([gene|01CE4BBBEB0C0855201D396FB8036F72B64EA7DD|ydbD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04430 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTACCCATCTCCTTTTT,  downstream forward: _UP4_TAAAGAGACAAGCCCAAAAC
• BKK04430 ([gene|01CE4BBBEB0C0855201D396FB8036F72B64EA7DD|ydbD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04430 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTACCCATCTCCTTTTT,  downstream forward: _UP4_TAAAGAGACAAGCCCAAAAC

References

• 15805528,10708364,11587647