ycgE

168

similar to transcription regulator

locus: BSU_03080

Molecular weight: 17.10 kDa

pI: 8.45

Protein length: 155 aa

Gene length: 465 bp

function: unknown

product: unknown

essential: no

ec: null

synonyms: ycgE

List of homologs in different organisms, belongs to COG1846 (Galperin et al., 2021)

Gene

Coordinates: 334,092 → 334,556

Phenotypes of a mutant

• improved survival after [category|SW.3.1.1|DNA replication] arrest imposed by inhibition of [protein|FB97DF0C147FB29944F60214CB9BC1803861DAA0|polC] activity [pubmed|36574412]

The protein

[wiki|Domains]

• [wiki|HTH marR-type domain] (aa 7-143) (according to UniProt)

Structure

• [PDB|4XRF] (from B. cereus, corresponds to aa 34 ... 136, 32.2% identity)
• [AF|O31472]

Expression and Regulation

Operons

• genes: [gene|D948867BAEF91943250714453A474B90AB64E523|ycgE]-[gene|78B3F9580DED32469ACF537F4B40C7DBF0D4D995|ycgF]-[gene|CBEC4D299232FC5FCB57211525404CBD42D5AF68|ycgG]

  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-C049 (ycgE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2047 NBRP B. subtilis, Japan]
• BKE03080 (Δ[gene|D948867BAEF91943250714453A474B90AB64E523|ycgE]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03080 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAACTGACAGTCCTCCCTAT,  downstream forward: _UP4_TAAGTGAATTTGTGCATAGC
• BKK03080 (Δ[gene|D948867BAEF91943250714453A474B90AB64E523|ycgE]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03080 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAACTGACAGTCCTCCCTAT,  downstream forward: _UP4_TAAGTGAATTTGTGCATAGC

References

• 36574412