yccK

168

similar to aldo/ ketoreductase

locus: BSU_02770

Molecular weight: 34.65 kDa

pI: 5.01

Protein length: 310 aa

Gene length: 933 bp

function: unknown

product: unknown

essential: no

synonyms: yccK, yzaE

List of homologs in different organisms, belongs to COG0667 (Galperin et al., 2021)

Gene

Coordinates: 298,466 → 299,398

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The protein

Protein family

• [wiki|Aldo/keto reductase family] (according to UniProt)
• [wiki|Aldo/keto reductase 2 subfamily] (according to UniProt)

Structure

• [PDB|1PZ0] ([protein|F1AFFACD36C75702B0BB8F0B4241A9688FB6253C|iolS], 53% identity) [Pubmed|15019785]
• [AF|P46905]

Paralogous protein(s)

• [protein|F1AFFACD36C75702B0BB8F0B4241A9688FB6253C|iolS], [protein|4DF9B105ABA64AFD5106EE75FCC9EFAB52BEFC83|yhdN]
• [protein|35E890DE5096DF603FC16EF5F2CDF329CE104690|yrpG], (31,4%)

Expression and Regulation

Operons

• genes: [gene|B73D729097C00BE6F3C7FF1708738783EE93C6FB|yccK]

  description: [Pubmed|17322186]

Biological materials

Mutant

• MGNA-B977 (yccK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1976 NBRP B. subtilis, Japan]
• BKE02770 (Δ[gene|B73D729097C00BE6F3C7FF1708738783EE93C6FB|yccK]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02770 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTGTTCCTTCTCCTTTGA,  downstream forward: _UP4_TAAAAAAGGAAATAGCCGTC
• BKK02770 (Δ[gene|B73D729097C00BE6F3C7FF1708738783EE93C6FB|yccK]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02770 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTGTTCCTTCTCCTTTGA,  downstream forward: _UP4_TAAAAAAGGAAATAGCCGTC

References

• 17322186