Transcription factors activating transcription at SigL-dependent promoters

These transcription activators control transcription at SigL-dependent promoters. RNA polymerase containing SigL is inactive unless productive interaction with an activator protein occurs. Therefore, SigL-dependent genes are among the most strongly regulated genes in B. subtilis.

Activators controlled by interaction with low molecular weight effectors

• AcoR: control of acetoin utilization (acoA-acoB-acoC-acoL)
• BkdR: control of the utilization of branched chain amino acids
• RocR: control of the utilization of arginine, ornithine and citrulline (rocA-rocB-rocC, rocD-rocE-rocF, rocG)

Activator controlled by PTS-dependent phosphorylation

• LevR: control of fructose utilization (levD-levE-levF-levG-sacC)

Unknown activator

• YplP: required for growth at low temperatures

Reviews

Nicolas Joly, Nan Zhang, Martin Buck, Xiaodong Zhang
Coupling AAA protein function to regulated gene expression.
Biochim Biophys Acta: 2012, 1823(1);108-16
[PubMed:21906631] [WorldCat.org] [DOI] (P p)

Victoria Shingler
Signal sensory systems that impact σ⁵⁴ -dependent transcription.
FEMS Microbiol Rev: 2011, 35(3);425-40
[PubMed:21054445] [WorldCat.org] [DOI] (I p)

L Lauren Beck, Todd G Smith, Timothy R Hoover
Look, no hands! Unconventional transcriptional activators in bacteria.
Trends Microbiol: 2007, 15(12);530-7
[PubMed:17997097] [WorldCat.org] [DOI] (P p)

David J Studholme, Ray Dixon
Domain architectures of sigma54-dependent transcriptional activators.
J Bacteriol: 2003, 185(6);1757-67
[PubMed:12618438] [WorldCat.org] [DOI] (P p)

E Morett, L Segovia
The sigma 54 bacterial enhancer-binding protein family: mechanism of action and phylogenetic relationship of their functional domains.
J Bacteriol: 1993, 175(19);6067-74
[PubMed:8407777] [WorldCat.org] [DOI] (P p)