tagG

168

ABC transporter for teichoic acid translocation (permease)

Locus: BSU_35710

Molecular weight: 32.03 kDa

Isoelectric point: 9.56

Protein length: 275 aa

Gene length: 828 bp

Function: Biosynthesis of teichoic acid

Product: ABC transporter for teichoic acid translocation (permease)

Essential: yes

Synonyms: tagG

Genomic Context

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Categories containing this gene/protein

Cellular processes, Cell envelope and cell division, Cell wall synthesis, Biosynthesis of teichoic acid

Cellular processes, Cell envelope and cell division, Cell wall synthesis, Export of anionic polymers and attachment to peptidoglycan

Cellular processes, Transporters, ABC transporters, Exporters, Export of cell wall components

Metabolism, Additional metabolic pathways, Biosynthesis of cell wall components, Biosynthesis of teichoic acid

Groups of genes, Essential genes

Groups of genes, Membrane proteins

List of homologs in different organisms, belongs to COG1682 (Galperin et al., 2021)

Gene

Coordinates: 3,675,167  3,675,994

Phenotypes of a mutant

essential PubMed

The protein

Protein family

ABC-2 integral membrane protein family (according to UniProt)

Domains

ABC transmembrane type-2 domain (aa 35-267) (according to UniProt)

Structure

6JBH (PDB) (the complex corresponding to TagG-TagH from Alicyclobacillus herbarius, 41.7% identity) PubMed
P42953 (AlphaFold)

Localization

cell membrane (according to UniProt)

Expression and Regulation

Operons

Genes: tagD-tagE-tagF-tagG-tagH

Description: PubMed

Regulation

repressed by phosphate (PhoP) PubMed

Regulatory mechanism

PhoP: repression, PubMed, in phoP regulon
WalR: activation, PubMed, in walR regulon

Sigma factors

SigA: sigma factor, PubMed, in sigA regulon

Biological materials

GFP fusion

3512 trpC2 tagG::pSG5322 (cat P_xyl-gfp-tagG1-346) PubMed, available in Dirk Jan Scheffers' lab and in the BGSC

References

Reviews

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Original Publications

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