sndC

168

sulphur compound N-deacetylase

Locus: BSU_10070

Molecular weight: 43.11 kDa

Isoelectric point: 5.86

Protein length: 396 aa

Gene length: 1191 bp

Function: unknown

Product: sulphur compound N-deacetylase

Essential: no

Synonyms: sndC, yhaA

Genomic Context

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Categories containing this gene/protein

Groups of genes, Poorly characterized/ putative enzymes

List of homologs in different organisms, belongs to COG1473 (Galperin et al., 2021)

Gene

Coordinates: 1,080,150 → 1,081,340

Phenotypes of a mutant

a ''sndA sndB sndC'' triple mutant does not grow with N-acetyl cysteine and S-(2-succino)cysteine as the single sources of sulfur PubMed

The protein

Protein family

peptidase M20A family (according to UniProt)

Structure

4EWT (PDB) (from Staphylococcus aureus, 43% identity) PubMed
O07598 (AlphaFold)

Paralogous protein(s)

YkuR, SndA
SndB, (38,8%)

Expression and Regulation

Operons

Genes: sndC

Description: PubMed

Regulation

repressed by casamino acids PubMed

Genes: yhfA-sndC

Description: PubMed

Biological materials

Mutant

MGNA-B500 (yhaA::erm), available at the NBRP B. subtilis, Japan
BKE10070 (ΔsndC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAGCCGCTTCCCCCTTTT,  downstream forward: _UP4_CTATAAAAAAACAGCCGGAG
BKK10070 (ΔsndC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAGCCGCTTCCCCCTTTT,  downstream forward: _UP4_CTATAAAAAAACAGCCGGAG

References

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