rimM

rimM
168

16S rRNA processing protein, RNase

locus
BSU_16020
Molecular weight
20.06 kDa
pI
5.22
Protein length
Gene length
function
maturation of 16S rRNA
product
16S rRNA processing protein, RNase
essential
no
synonyms
rimM, ylqE

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0806 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,674,650  1,675,174
Phenotypes of a mutant
the mutant tends to acquire suppressor mutations that result in improved growth [Pubmed|28189581]
defective in 16S rRNA 3' processing by [protein|E0437C86E5F3707FF1DA13C8B98F73130DED8FB4|yqfG] [pubmed|31003868]
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The protein
Protein family
RimM family (single member, according to UniProt)
[wiki|Domains]
PRC barrel domain (aa 98-171) (according to UniProt)
Structure
[PDB|3H9N] (from ''Haemophilus influenzae'', 33% identity)
[AF|O31740]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]-[gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh]-[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]-[gene|67FB5F6FB0B2701BD8E4FDD8DF06B236DE6A2599|khpA]-[gene|0AB1FB44E8F28944B82B5EF14A9CDCFEE46DB76B|ylqD]-[gene|34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498|rimM]-[gene|885ECD9FAAC8BC95D32F049825D6B6244C046112|trmD]-[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]
description
[Pubmed|29794222]
regulation
the mRNA is processed between [gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh] and [gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|ricA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|ricF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|ricT] complex [Pubmed|29794222]
expression
expression is decreased upon depletion of tRNA maturation factors [gene|57A79AAF00243B5E058FA901D43AA7B55CA33F63|rnpB] or [gene|C40C5D35ED53D343C8200248FCCB010BAB388054|rnz] [pubmed|36840557]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8335643], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Open in new tab

[gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]→[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]

2024-02-07 15:26:05

Jstuelk

82

4F2FF9A3B937EE85312D0B0F9DA494E4B44E2297

417C7007C2492335257F8AEF606BB8627753757F

genes
[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]-[gene|67FB5F6FB0B2701BD8E4FDD8DF06B236DE6A2599|khpA]-[gene|0AB1FB44E8F28944B82B5EF14A9CDCFEE46DB76B|ylqD]-[gene|34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498|rimM]-[gene|885ECD9FAAC8BC95D32F049825D6B6244C046112|trmD]-[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]
description
[Pubmed|36840557]
Open in new tab

[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]→[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]

2024-03-07 02:42:46

Jstuelk

29

B00427AA69EF576CAC3B8B5C44347F99001CAF0D

B00427AA69EF576CAC3B8B5C44347F99001CAF0D

genes
[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]-[gene|67FB5F6FB0B2701BD8E4FDD8DF06B236DE6A2599|khpA]-[gene|0AB1FB44E8F28944B82B5EF14A9CDCFEE46DB76B|ylqD]-[gene|34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498|rimM]
description
[Pubmed|36840557]
Open in new tab

[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]→[gene|34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498|rimM]

2024-03-27 00:28:38

Jstuelk

24

B1D4FB4E8DDCF0CB0481B85ABEADC1254ACBB0DF

B1D4FB4E8DDCF0CB0481B85ABEADC1254ACBB0DF

Biological materials
Mutant
MGNA-B376 (ylqE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1375 NBRP B. subtilis, Japan]
BKE16020 ([gene|34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498|rimM]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE16020 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATGATCACCTCTGGCGA,  downstream forward: _UP4_GAATGAAAATCGATTTTTTG
BKK16020 ([gene|34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498|rimM]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK16020 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATGATCACCTCTGGCGA,  downstream forward: _UP4_GAATGAAAATCGATTTTTTG
References
36815589,15496525,31003868,36840557

34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498

Page visits: 2682

Time of last update: 2024-03-28 19:24:16

Author of last update: Christoph.elfmann