PASTA domain

Penicillin-binding protein and serine/threonine kinase associated domain, binds muropeptides

In B. subtilis, this domain is present in the following proteins:

• PBP2B
• PrkC
• SpoVD

References

Daniel A Pensinger, Adam J Schaenzer, John-Demian Sauer
Do Shoot the Messenger: PASTA Kinases as Virulence Determinants and Antibiotic Targets.
Trends Microbiol: 2018, 26(1);56-69
[PubMed:28734616] [WorldCat.org] [DOI] (I p)

Ewa Bukowska-Faniband, Lars Hederstedt
The PASTA domain of penicillin-binding protein SpoVD is dispensable for endospore cortex peptidoglycan assembly in Bacillus subtilis.
Microbiology (Reading): 2015, 161(Pt 2);330-340
[PubMed:25481876] [WorldCat.org] [DOI] (I p)

Corin Yeats, Robert D Finn, Alex Bateman
The PASTA domain: a beta-lactam-binding domain.
Trends Biochem Sci: 2002, 27(9);438
[PubMed:12217513] [WorldCat.org] [DOI] (P p)

C Goffin, J M Ghuysen
Multimodular penicillin-binding proteins: an enigmatic family of orthologs and paralogs.
Microbiol Mol Biol Rev: 1998, 62(4);1079-93
[PubMed:9841666] [WorldCat.org] [DOI] (P p)