mrpE

168

Na⁺/H⁺ antiporter subunit, multiple resistance and pH homeostasis

locus: BSU_31640

Molecular weight: 18.04 kDa

pI: 8.12

Protein length: 158 aa

Gene length: 477 bp

function: sodium export

product: Na⁺/H⁺ antiporter subunit

essential: yes

synonyms: mrpE

List of homologs in different organisms, belongs to COG1863 (Galperin et al., 2021)

Gene

Coordinates: 3,251,248 → 3,251,724

Phenotypes of a mutant

• essential [Pubmed|28189581]

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The protein

Protein family

• CPA3 antiporters (TC 2.A.63) subunit E family (single member, according to UniProt)

Structure

• [AF|Q7WY60]

[wiki|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|E968DECF869CAF7E247A518494AD70B554A7A25F|mrpA]-[gene|AAB15E7E3E3701AA3159370B85C151994244BA5B|mrpB]-[gene|D921139B18A665E9BB177C973FCF050A4BFFF97F|mrpC]-[gene|051D9BCC0CB05E39ED5825BB9BA77B8228EA055D|mrpD]-[gene|BF233467FAF95EEEE12A0D36C543DB357D8879EA|mrpE]-[gene|5CA2EA2D60FE4696903C16698C8329A20CBEBF72|mrpF]-[gene|B28796716C7E6C924F55176453DDBF9ADD0EF755|mrpG]

  description: [Pubmed|9274030,10198001]

References

Reviews

• 29218041

Original Publications

• 11004162,17693497,10198001,26588577,26582911,28189581,18408029