mpr

168

extracellular metalloprotease

locus: BSU_02240

Molecular weight: 33.69 kDa

pI: 8.97

Protein length: 313 aa

Gene length: 942 bp

function: protein degradation

product: extracellular metalloprotease

essential: no

synonyms: mpr

List of homologs in different organisms, belongs to COG3591 (Galperin et al., 2021)

Gene

Coordinates: 245,190  246,131

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The protein

Protein family

• peptidase S1B family (single member, according to UniProt)

Structure

• [PDB|1P3C] (from B. intermedius, corresponds to aa 95 ... 289, 31% identity) [pubmed|15005613]
• [AF|P39790]

[wiki|Localization]

• extracellular (signal peptide) [Pubmed|18957862]

Biological materials

Mutant

• KO7 (''nprE  aprE  epr  mpr  nprB  vpr  bpr''), available as BGSC 1A1133
• BKE02240 ([gene|A39D349BBE13F4F3F6D33DA72CB8149A5170255C|mpr]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02240 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTGTCATCTCCCTCCT,  downstream forward: _UP4_AACTTGGGAACAAGGGTGAC
• BKK02240 ([gene|A39D349BBE13F4F3F6D33DA72CB8149A5170255C|mpr]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02240 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTGTCATCTCCCTCCT,  downstream forward: _UP4_AACTTGGGAACAAGGGTGAC

References

Reviews

• 34410368

Original Publications

• 15375126,24115457,18957862,12107147,25666135,15005613