lrpB

168

transcriptional regulator ([wiki|Lrp family]) involved in repression of [gene|BAE8062DA8538C9C83FFBA9684BECE9613EEFD2F|glyA] transcription and [protein|2111AC1AE49D1006E10DC127BF5B7A0327DE94A7|kinB]-dependent [wiki|sporulation]

locus: BSU_05060

Molecular weight: 17.18 kDa

pI: 6.68

Protein length: 149 aa

Gene length: 450 bp

function: repression of [gene|BAE8062DA8538C9C83FFBA9684BECE9613EEFD2F|glyA] transcription and [protein|2111AC1AE49D1006E10DC127BF5B7A0327DE94A7|kinB]-dependent [wiki|sporulation]

product: transcription regulator ([wiki|Lrp family])

essential: no

synonyms: lrpB, yddP

List of homologs in different organisms, belongs to COG1522 (Galperin et al., 2021)

Gene

Coordinates: 552,052  552,501

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The protein

Protein family

• ([wiki|Lrp family])

[wiki|Domains]

• [wiki|HTH asnC-type domain] (aa 3-64) (according to UniProt)

Structure

• [PDB|2CFX] ([protein|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC], 31% identity) [pubmed|16528101]
• [AF|P96653]

Biological materials

Mutant

• MGNA-C110 (yczA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2108 NBRP B. subtilis, Japan]
• BKE05060 ([gene|1437D66EABB5D7FF4F8B9EBAD624510D86F0C8B4|lrpB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05060 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAGTAACTCCTTTCACAG,  downstream forward: _UP4_TAATGCGCTTGTTATTATAA
• BKK05060 ([gene|1437D66EABB5D7FF4F8B9EBAD624510D86F0C8B4|lrpB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05060 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAGTAACTCCTTTCACAG,  downstream forward: _UP4_TAATGCGCTTGTTATTATAA

References

Research papers

• 16528101