hutU

168

urocanase

locus: BSU_39360

Molecular weight: 60.43 kDa

pI: 5.66

Protein length: 552 aa

Gene length: 1659 bp

function: histidine utilization

product: urocanase

essential: no

ec: 4.2.1.49

synonyms: hutU

List of homologs in different organisms, belongs to COG2987 (Galperin et al., 2021)

Gene

Coordinates: 4,043,574 → 4,045,232

Advertisement

The protein

Catalyzed reaction/ biological activity

• 4-imidazolone-5-propanoate --> H₂O + trans-urocanate (according to UniProt)

Protein family

• urocanase family (single member, according to UniProt)

Structure

• [PDB|2FKN]
• [AF|P25503]

[wiki|Localization]

• cytoplasm (according to Swiss-Prot)

Biological materials

Mutant

• BKE39360 (Δ[gene|ED6002BB56B96F9A2B4F80CA050518B266000E55|hutU]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE39360 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_AGTCATATGTTCATCCCCCT,  downstream forward: _UP4_ATGCAAAAATAAAGGAGTGA
• BKK39360 (Δ[gene|ED6002BB56B96F9A2B4F80CA050518B266000E55|hutU]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK39360 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_AGTCATATGTTCATCCCCCT,  downstream forward: _UP4_ATGCAAAAATAAAGGAGTGA

References

Reviews

• 22933560

Original Publications

• 10746760,8071225,8682780,10217782,21821766