frlM

168

aminosugar [wiki|ABC transporter] (permease)

locus: BSU_32580

Molecular weight: 34.00 kDa

pI: 7

Protein length: 300 aa

Gene length: 903 bp

function: uptake of sugar amines

product: aminosugar [wiki|ABC transporter] (permease)

essential: no

synonyms: frlM, yurM

List of homologs in different organisms, belongs to COG0395 (Galperin et al., 2021)

Gene

Coordinates: 3,347,919  3,348,821

Advertisement

The protein

Protein family

• [wiki|Binding-protein-dependent transport system permease family] (according to UniProt)
• [wiki|MalFG subfamily] (according to UniProt)

[wiki|Domains]

• [wiki|ABC transmembrane type-1 domain] (aa 94-285) (according to UniProt)

Structure

• [PDB|2R6G] (from E. coli, corresponds to aa 96 ... 300, 36% identity) [pubmed|18033289]
• [AF|O32154]

[wiki|Localization]

• cell membrane [Pubmed|10092453]

Biological materials

Mutant

• MGNA-A559 (yurM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/559 NBRP B. subtilis, Japan]
• BKE32580 ([gene|1F245030D0C81DC96FC0642199CA00579CF46D06|frlM]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE32580 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TGTCTTCTTCTGAGGCAGCA,  downstream forward: _UP4_GTAAAAGGATAAAGGAGGAA
• BKK32580 ([gene|1F245030D0C81DC96FC0642199CA00579CF46D06|frlM]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK32580 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TGTCTTCTTCTGAGGCAGCA,  downstream forward: _UP4_GTAAAAGGATAAAGGAGGAA

References

• 23175651,21815947,12618455,10092453,21347729,21398478,18033289,36815589