EfeO

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  • Description: lipoprotein, elemental iron uptake system (binding protein), high affinity uptake of ferric iron (Fe(III))

Gene name ywbM
Synonyms ipa-28d
Essential no
Product elemental iron uptake system (binding protein)
Function elemental iron uptake
Gene expression levels in SubtiExpress: efeO
Interactions involving this protein in SubtInteract: EfeO
Metabolic function and regulation of this protein in SubtiPathways:
EfeO
MW, pI 42 kDa, 4.712
Gene length, protein length 1155 bp, 385 aa
Immediate neighbours efeB, efeU
Sequences Protein DNA DNA_with_flanks
Genetic context
YwbM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YwbM expression.png















Categories containing this gene/protein

transporters/ other, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

  • Locus tag: BSU38270

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • binds ferric iron (Fe(III)) with strong selectivity PubMed
  • Protein family: UPF0409 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 1047 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 2113 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References