dppE

168

dipeptide [wiki|ABC transporter] (dipeptide-binding protein)

locus: BSU_12960

Molecular weight: 62.41 kDa

pI: 5.52

Protein length: 549 aa

Gene length: 1650 bp

function: uptake of dipeptides

product: dipeptide [wiki|ABC transporter] (dipeptide-binding protein)

essential: no

synonyms: dppE, dciAE

List of homologs in different organisms, belongs to COG4166 (Galperin et al., 2021)

Gene

Coordinates: 1,364,151  1,365,800

Advertisement

The protein

Protein family

• [wiki|bacterial solute-binding protein 5 family] (according to UniProt)

Structure

• [PDB|8AZB] [pubmed|36748525]
• [PDB|4FAJ] (from Enterococcus faecalis, 33% identity) [pubmed|22948145]
• [AF|P26906]

Paralogous protein(s)

• [protein|302DFA46D73E18C4663468ED6033C55056744475|oppA]

[wiki|Localization]

• attached to the cell membrane (via [protein|062AE5FB4C778178A7F6833CB8BD9D631E461E89|dppB]-[protein|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]) [Pubmed|10092453,18763711]

Biological materials

Mutant

• GP1110 (spc), available in [wiki|Jörg Stülke]'s lab
• 1A737 ( ''dppE''::''kan''), [Pubmed|1766370], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A737&Search=1A737 BGSC]
• BKE12960 ([gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE12960 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCTCTTCCCCCTTTTCA,  downstream forward: _UP4_TGATGGAGGCGATTGAGGAA
• BKK12960 ([gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK12960 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCTCTTCCCCCTTTTCA,  downstream forward: _UP4_TGATGGAGGCGATTGAGGAA

References

• 12618455,10092453,1766371,7783641,1766371,18763711,22948145,36748525