csoR

csoR
168

transcription repressor of [gene|18506FB74F6BB9278F22EB7DCDA3CF72575CC32A|copZ]-[gene|727024F7B1AC19676ED4B516CF46A47B1328310B|copA]

locus
BSU_33520
Molecular weight
11.34 kDa
pI
7.3
Protein length
Gene length
function
control of copper homeostasis
product
transcription repressor
essential
no
synonyms
csoR, yvgZ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1937 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,443,896  3,444,201
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The protein
Protein family
CsoR family (single member, according to UniProt)
Structure
[PDB|4M1P] (from Geobacillus thermodenitrificans, 59% identity) [pubmed|24831014]
[AF|O32222]
Effectors of protein activity
Cu(I) ions cause release of CsoR from its operator sites
Expression and Regulation
Operons
genes
[gene|6977F18870004AD236539D9409255815E6BE9241|csoR]-[gene|18506FB74F6BB9278F22EB7DCDA3CF72575CC32A|copZ]-[gene|727024F7B1AC19676ED4B516CF46A47B1328310B|copA]
description
[Pubmed|22383849]
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[gene|6977F18870004AD236539D9409255815E6BE9241|csoR]→[gene|727024F7B1AC19676ED4B516CF46A47B1328310B|copA]

2024-03-14 11:08:52

Jstuelk

59

eb86b49e4fa20367c75145f1a228f37db4b5da04

AAFF284B2BD1673523D4C48EA1D3231D7A156AFC

Biological materials
Mutant
MGNA-B604 (yvgZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1603 NBRP B. subtilis, Japan]
BKE33520 ([gene|6977F18870004AD236539D9409255815E6BE9241|csoR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33520 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGCGTACACCTCTGTTTA,  downstream forward: _UP4_TAAAGCGTTTTTTATTGTAA
BKK33520 ([gene|6977F18870004AD236539D9409255815E6BE9241|csoR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33520 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGCGTACACCTCTGTTTA,  downstream forward: _UP4_TAAAGCGTTTTTTATTGTAA
labs
[wiki|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
[wiki|Mohamed Marahiel], Marburg University, Germany [http://www.uni-marburg.de/fb15/fachgebiete/bio/marahiel?language_sync=1 homepage]
References
Reviews
22918892,25209494
Original Publications
18048925,19168619,20233928,19168619,19249860,24831014

6977F18870004AD236539D9409255815E6BE9241

Page visits: 2704

Time of last update: 2024-03-28 10:12:28

Author of last update: Melvin.boenninger