coxA

168

spore cortex lipoprotein

locus: BSU_27830

Molecular weight: 19.39 kDa

pI: 9.22

Protein length: 198 aa

Gene length: 597 bp

function: resistance of the spore

product: spore cortex protein

essential: no

ec: null

synonyms: coxA, yrbB

List of homologs in different organisms, belongs to COG5912 (Galperin et al., 2021)

Gene

Coordinates: 2,843,931  2,844,527

Phenotypes of a mutant

• defective in [protein|search|GerA]-mediated germination triggered by addition of L-valine [pubmed|37338384]

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The protein

Structure

• [AF|P94446]

Expression and Regulation

Operons

• genes: [gene|CEBEC9CECCF445C40D793E61A2CD23175631A473|safA]-[gene|6EAB09018D9AF9C488E713C232CD77B63415DCE3|coxA]

  description: [Pubmed|10438771]

  regulation

  • expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|10438771]

  sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|10438771], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]

Biological materials

Mutant

• MGNA-A010 (yrbB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/10 NBRP B. subtilis, Japan]
• BKE27830 ([gene|6EAB09018D9AF9C488E713C232CD77B63415DCE3|coxA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE27830 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATGGAAAAACCCCCCGTG,  downstream forward: _UP4_TAGGAAGGAAGGGCTGCCGG
• BKK27830 ([gene|6EAB09018D9AF9C488E713C232CD77B63415DCE3|coxA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK27830 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATGGAAAAACCCCCCGTG,  downstream forward: _UP4_TAGGAAGGAAGGGCTGCCGG

References

• 10438771,37338384