cotZ

cotZ
168

spore crust anchor protein, necessary for the assembly of the spore crust, the outermost layer of the spore coat

locus
BSU_11740
Molecular weight
16.00 kDa
pI
5
Protein length
Gene length
function
spore crust assembly
product
spore crust anchor protein
essential
no
synonyms
cotZ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5888 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,249,442 → 1,249,888
Phenotypes of a mutant
mis-assembly of the spore crust [Pubmed|22171814]
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The protein
Catalyzed reaction/ biological activity
required for the localization of most crust proteins [pubmed|30582883]
Structure
[AF|Q08312]
Paralogous protein(s)
[protein|B2636947990A303C43CEA8BFBE38811DD233A0A6|cotY]
[wiki|Localization]
outermost layer of the spore coat (crust), localization depends on [protein|825AD8D4315A85CD384F9AF6AD894E38E57C88F7|cotE] [Pubmed|22171814]
more abundant at the mother cell-proximal pole of the forespore  [Pubmed|19933362,21665972]
Expression and Regulation
Operons
genes
[gene|B2636947990A303C43CEA8BFBE38811DD233A0A6|cotY]-[gene|B3BA3A44C3EE2747FB594BD7199864E9ECA953CB|cotZ]
description
[Pubmed|7519271]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|7519271,15699190]
regulatory mechanism
[protein|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]: activation, [Pubmed|15621419], in [regulon|protein:0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR regulon]
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|7519271], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|7519271,15699190], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|26577401,15383836], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
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[gene|B2636947990A303C43CEA8BFBE38811DD233A0A6|cotY]→[gene|B3BA3A44C3EE2747FB594BD7199864E9ECA953CB|cotZ]

2024-02-16 11:39:01

ghost

33

d5352cc528c9d84dd78f9c0efc66e2b6f4d516ce

FC77A0E4A305752E4BFB18C6B5B61BE0A0A39C5D

Biological materials
Mutant
BKE11740 (Δ[gene|B3BA3A44C3EE2747FB594BD7199864E9ECA953CB|cotZ]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE11740 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATTATCCCTCCTGCCTT,  downstream forward: _UP4_TAATCATAAGCTGGAAAAGC
BKK11740 (Δ[gene|B3BA3A44C3EE2747FB594BD7199864E9ECA953CB|cotZ]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK11740 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATTATCCCTCCTGCCTT,  downstream forward: _UP4_TAATCATAAGCTGGAAAAGC
References
Reviews
22192522,23202530,27227299
Original Publications
19304857,7519271,15699190,19933362,20451384,21665972,22171814,15383836,26341943,15621419,27320701,28870294,30582883,31502725,33596081

B3BA3A44C3EE2747FB594BD7199864E9ECA953CB

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Time of last update: 2024-03-18 19:48:03

Author of last update: Jstuelk