cotP

cotP
168

inner spore coat protein

locus
BSU_05550
Molecular weight
16.91 kDa
pI
4.56
Protein length
Gene length
function
resistance of the spore
product
inner spore coat protein
essential
no
synonyms
cotP, ydfT

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0071 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
601,741  602,172
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The protein
Protein family
[wiki|small heat shock protein (Hsp20) family] (according to UniProt)
[wiki|Domains]
sHSP domain (aa 34-143) (according to UniProt)
Structure
[AF|P96698]
[wiki|Localization]
inner spore coat, localization depends on [protein|CEBEC9CECCF445C40D793E61A2CD23175631A473|safA]  [Pubmed|22171814]
Expression and Regulation
Operons
genes
[gene|68E585F6670539982E8E8032337DA2043C67FCC4|ydgB]-[gene|483587EB658850D786C3C95C02D419994FCC9F45|ydgA]-[gene|8F85E6DE353F29759301A463335BFC15F829E2D0|cotP]
description
[Pubmed|22383849]
regulation
expressed during sporulation ([protein|6FAD8804AA32B84819DDE57C0AF63F208FB9FFD1|sigKC]) [Pubmed|15699190]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: repression, [Pubmed|9068633], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
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[gene|68E585F6670539982E8E8032337DA2043C67FCC4|ydgB]→[gene|8F85E6DE353F29759301A463335BFC15F829E2D0|cotP]

2024-03-14 22:16:20

Jstuelk

47

de48ea4783cd7cf077418358a047c717f33b726d

B2B75FA92D67D5FD8246AB165C9B607A031D1E77

Biological materials
Mutant
MGNA-C172 (ydfT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2170 NBRP B. subtilis, Japan]
BKE05550 ([gene|8F85E6DE353F29759301A463335BFC15F829E2D0|cotP]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05550 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATGAGATTCTCCTTAAA,  downstream forward: _UP4_GGGCTTTAAGATTGATTGTT
BKK05550 ([gene|8F85E6DE353F29759301A463335BFC15F829E2D0|cotP]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05550 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATGAGATTCTCCTTAAA,  downstream forward: _UP4_GGGCTTTAAGATTGATTGTT
References
11150673,15699190,9068633,22171814,26187959

8F85E6DE353F29759301A463335BFC15F829E2D0

Page visits: 3183

Time of last update: 2024-03-19 07:53:58

Author of last update: Melvin.boenninger