cotB

cotB
168

spore coat protein (outer)

locus
BSU_36050
Molecular weight
42.81 kDa
pI
9.83
Protein length
Gene length
function
resistance of the spore
product
spore coat protein (outer)
essential
no
synonyms
cotB

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
3,714,739  3,715,881
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The protein
Structure
[AF|P07789]
Modification
phosphorylated on serine residues by [protein|D53067098F693669F61E5CCF6C06664580C40C79|cotH] [Pubmed|27185916]
maturation of CotB requires [protein|49BAFE3E69F1F91AEF4154F55B44639DD3CE4A71|cotG] [Pubmed|26953338]
[wiki|Localization]
outer spore coat, at the middle of the spore as a ring- or spiral-like structure, localization depends on [protein|825AD8D4315A85CD384F9AF6AD894E38E57C88F7|cotE]  [Pubmed|22171814,19933362]
Expression and Regulation
Operons
genes
[gene|D53067098F693669F61E5CCF6C06664580C40C79|cotH]-[gene|2A0B2CA7C982C03C1AFBDB3540A918EE937B06CB|cotB]-[gene|61004D2C1EDA3CD84514FD6D468BF594575616F4|ywrJ]
description
[Pubmed|22383849]
regulation
expressed late during sporulation in the mother cell ([wiki|SigE], [protein|search|SigK], [protein|search|GerE], [wiki|SpoIIID]) [Pubmed|26577401,15699190,8755863,15470121]
regulatory mechanism
[protein|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]: activation, [Pubmed|20435725], in [regulon|protein:0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR regulon]
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: repression, [Pubmed|15470121], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: activation, [Pubmed|26577401], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190,8755863,1691789,12480901], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15383836], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Open in new tab

[gene|D53067098F693669F61E5CCF6C06664580C40C79|cotH]→[gene|61004D2C1EDA3CD84514FD6D468BF594575616F4|ywrJ]

2024-03-13 23:00:51

ghost

66

522d2dc3540a057ccb4247a51bdcef8f2aab470a

03DF2C1A39CB01A4DB9919D07A586C7F244BEAFF

genes
[gene|2A0B2CA7C982C03C1AFBDB3540A918EE937B06CB|cotB]-[gene|61004D2C1EDA3CD84514FD6D468BF594575616F4|ywrJ]
description
[Pubmed|22383849]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE], [protein|search|GerR]) [Pubmed|15699190,1691789,15383836,20435725]
Open in new tab

[gene|2A0B2CA7C982C03C1AFBDB3540A918EE937B06CB|cotB]→[gene|61004D2C1EDA3CD84514FD6D468BF594575616F4|ywrJ]

2024-02-16 15:35:01

ghost

34

e1a7dfcab37c895cf68952c400b3c5dda66e8c33

70EF1AF9FFB64263BEFC2CDD5247BE6F97FE1D3F

Biological materials
Mutant
1S102 ( ''cotB''::''cat''), [Pubmed|2821284], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S102&Search=1S102 BGSC]
BKE36050 ([gene|2A0B2CA7C982C03C1AFBDB3540A918EE937B06CB|cotB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE36050 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCAAATTCCTCCTAGTC,  downstream forward: _UP4_TAATAGATAATGGAGGAGCA
BKK36050 ([gene|2A0B2CA7C982C03C1AFBDB3540A918EE937B06CB|cotB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK36050 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCAAATTCCTCCTAGTC,  downstream forward: _UP4_TAATAGATAATGGAGGAGCA
References
22171814,19933362,1518043,2821284,14762006,1691789,19933362,15699190,20435725,15383836,25259857,26953338,27185916,32592201

2A0B2CA7C982C03C1AFBDB3540A918EE937B06CB

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Time of last update: 2024-03-19 05:34:26

Author of last update: Jstuelk