corA

corA
168

general stress protein, similar to magnesium transporter

locus
BSU_24740
Molecular weight
37.55 kDa
pI
9.54
Protein length
Gene length
function
unknown
product
unknown
essential
no
synonyms
corA, yqhC, yqxL

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0598 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,560,489 → 2,561,442
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The protein
Catalyzed reaction/ biological activity
there is no indication for an implication of [protein|F0CACEFB53F4BC38DF77A38C4D78BA3DBE96E21A|corA] in Mg2 uptake (based on mutant phenotypes, failure to complement mutants defective in Mg2 uptake) [Pubmed|24415722]
Protein family
CorA metal ion transporter (MIT) (TC 1.A.35) family (together with [protein|D281B88EC444F8175AB50FB2CD24B51F4E2C96F8|yfjQ]) (according to UniProt)
Structure
[PDB|5JTG] (from Themotoga maritima, C-terminal domain, aa 122-297, 28% identity)
[AF|P40948]
[wiki|Localization]
inner spore membrane [Pubmed|26731423]
Expression and Regulation
Operons
genes
[gene|F0CACEFB53F4BC38DF77A38C4D78BA3DBE96E21A|corA]
description
[Pubmed|2507524]
regulation
induced by stress ([protein|search|SigB]) [Pubmed|15805528]
regulatory mechanism
[protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA]: repression, [Pubmed|16267290], in [regulon|protein:D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA regulon]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
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[gene|F0CACEFB53F4BC38DF77A38C4D78BA3DBE96E21A|corA]

2024-03-04 20:41:47

ghost

34

dad9929632067584005f4f6538b96b0d2c66005a

C63DF20DE434F8245D920A449446202051477C4A

Biological materials
Mutant
MGNA-C473 (yqxL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2471 NBRP B. subtilis, Japan]
BKE24740 (Δ[gene|F0CACEFB53F4BC38DF77A38C4D78BA3DBE96E21A|corA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE24740 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTCAAGCTCCTCCAAAC,  downstream forward: _UP4_TAGGATGTTTCATATTTTGT
BKK24740 (Δ[gene|F0CACEFB53F4BC38DF77A38C4D78BA3DBE96E21A|corA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK24740 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTCAAGCTCCTCCAAAC,  downstream forward: _UP4_TAGGATGTTTCATATTTTGT
References
Reviews
24079267
Original Publications
15231793,15856219,2507524,16267290,15805528,24415722,26731423,35129435

F0CACEFB53F4BC38DF77A38C4D78BA3DBE96E21A

Page visits: 2719

Time of last update: 2024-03-19 01:42:15

Author of last update: Jstuelk