cheR

cheR
168

MCPs methyltransferase

locus
BSU_22720
Molecular weight
29.80 kDa
pI
9.25
Protein length
Gene length
function
motility, chemotaxis
product
MCPs methyltransferase
essential
no
ec
2.1.1.80
synonyms
cheR

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1352 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,380,347  2,381,117
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The protein
Catalyzed reaction/ biological activity
methylation of specific glutamate residues in the cytoplasmic domain of methyl-accepting chemotactic protein receptors (MCPRs)
L-glutamyl-[protein] + S-adenosyl-L-methionine --> [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine (according to UniProt)
[wiki|Domains]
CheR-type methyltransferase domain (aa 1-256) (according to UniProt)
Structure
[PDB|5FTW] (complex with S-adenosyl-L-homocysteine)
[AF|P31105]
Expression and Regulation
Operons
genes
[gene|1217807AE3AE3A654BA0DD4AF5ADF1CEE62632B6|cheR]-[gene|9712D0E655289C97315314BDEE1A0DF2ED2ADCA2|aroF]-[gene|58B782C1F7931F8671161455E65E3D5C72B0BB9C|aroB]-[gene|5C2F7F9F5FCBFEDF77AC41725EFDA0FAF0FC3BC1|aroH]
description
[pubmed|22383849]
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[gene|1217807AE3AE3A654BA0DD4AF5ADF1CEE62632B6|cheR]→[gene|5C2F7F9F5FCBFEDF77AC41725EFDA0FAF0FC3BC1|aroH]

2024-03-16 00:20:31

Jstuelk

100

88965d20d1da4832592c311cace3ecbf90c44644

85AFABBE9DF5093CCB38A8A7CAF16B0DE8C014A7

Biological materials
Mutant
1A830 ( ''cheR''::''cat''), [Pubmed|8244966], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A830&Search=1A830 BGSC]
BKE22720 ([gene|1217807AE3AE3A654BA0DD4AF5ADF1CEE62632B6|cheR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22720 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTCTACTCTCCCAGTCT,  downstream forward: _UP4_TAGACTGACTTTTTGCTGAA
BKK22720 ([gene|1217807AE3AE3A654BA0DD4AF5ADF1CEE62632B6|cheR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22720 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTCTACTCTCCCAGTCT,  downstream forward: _UP4_TAGACTGACTTTTTGCTGAA
References
Reviews
20122866
Original Publications
8866475,21515776,25799883,27544050

1217807AE3AE3A654BA0DD4AF5ADF1CEE62632B6

Page visits: 1571

Time of last update: 2024-03-19 08:35:23

Author of last update: Melvin.boenninger