bofC
168
general stress protein, controls processing of pro-[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK] by [protein|8801B095C2CE36F3E0B9DBBF489FFB217087DC0A|spoIVFB]
locus
BSU_27750
Molecular weight
19.15 kDa
pI
5.75
function
control of processing of pro-[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK] by [protein|8801B095C2CE36F3E0B9DBBF489FFB217087DC0A|spoIVFB]
product
forespore regulator of the [protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigma-K] checkpoint
essential
no
ec
null
synonyms
bofC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5849 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,836,909 2,837,421
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The protein
Structure
[PDB|2BW2]
[AF|O05391]
Expression and Regulation
Operons
genes
[gene|12B260DBC4E29151364251837FD227593D0BF391|csbX]-[gene|A2C94BB9272407B305B90151F77835BB90414D0F|bofC]
description
[Pubmed|9099855]
regulation
expressed during sporulation in the forespore ([protein|search|SigF], [protein|search|SigG]) [Pubmed|16497325,9099855]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|22900538], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [Pubmed|15699190,9099855], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|9099855], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224,9099855], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
Biological materials
Mutant
BKE27750 ([gene|A2C94BB9272407B305B90151F77835BB90414D0F|bofC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE27750 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACCCTCTACACCTCTTTGC, downstream forward: _UP4_TAGCGTCCGCTGATTGAAGA
BKK27750 ([gene|A2C94BB9272407B305B90151F77835BB90414D0F|bofC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK27750 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACCCTCTACACCTCTTTGC, downstream forward: _UP4_TAGCGTCCGCTGATTGAAGA
References
Reviews
Original Publications
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Time of last update: 2024-04-25 22:37:29
Author of last update: Jstuelk