alaR

168

transcriptional regulator ([wiki|Lrp family]) of the [gene|1CA87275AFA1B4E4B5E8E10229009F785E70BBA8|alaR]-[gene|62A9CD9AF72D0A48EC5ABC1585E2D8636D36D021|alaT] operon

locus: BSU_31410

Molecular weight: 18.62 kDa

pI: 4.89

Protein length: 166 aa

Gene length: 501 bp

function: unknown

product: transcription regulator ([wiki|Lrp family])

essential: no

synonyms: alaR, yugG

List of homologs in different organisms, belongs to COG1522 (Galperin et al., 2021)

Gene

Coordinates: 3,226,933  3,227,433

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The protein

Protein family

• ([wiki|Lrp family])

[wiki|Domains]

• [wiki|HTH asnC-type domain] (aa 3-65) (according to UniProt)

Structure

• [AF|O05236]

Modification

• phosphorylated on Arg-79 [Pubmed|22517742]

Expression and Regulation

Operons

• genes: [gene|1CA87275AFA1B4E4B5E8E10229009F785E70BBA8|alaR]-[gene|62A9CD9AF72D0A48EC5ABC1585E2D8636D36D021|alaT]

  description: [Pubmed|22383849]

  additional information

  • A [protein|search|ncRNA] is predicted between [gene|B0908BB4B8B569A7A78BB0B84784FD4C427C598B|yugI] and [gene|62A9CD9AF72D0A48EC5ABC1585E2D8636D36D021|alaT] [PubMed|20525796]

Biological materials

Mutant

• MGNA-A622 (yugG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/622 NBRP B. subtilis, Japan]
• BKE31410 ([gene|1CA87275AFA1B4E4B5E8E10229009F785E70BBA8|alaR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31410 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTGATTCACACCTTTGC,  downstream forward: _UP4_AAAAGAATCGTGGTGTCACC
• BKK31410 ([gene|1CA87275AFA1B4E4B5E8E10229009F785E70BBA8|alaR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31410 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTGATTCACACCTTTGC,  downstream forward: _UP4_AAAAGAATCGTGGTGTCACC

References

• 36815589,22517742,22383849