SubtiBank SubtiBank
rpsO operon
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rpsO operon


regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]
  • regulation

  • translational repression of ''rpsO'' expression upon binding of excess [protein|EC5D3ECF361C7CDEB606284F5E17243CD926989E|RpsO] to a [SW|RNA switch] in the untranslated region of the ''rpsO'' mRNA [Pubmed|23611891,16005889]
  • additional information

  • the mRNA is processed, this is initiated by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] and cleavage products are subsequently subject to exonucleolytic degradation by RNases [protein|3EB289D0F58A58C693AB588798EE66A731341999|J1] and [protein|B73CE26E7AEFACFA82C67F3E7DBBB3F766F739CA|J2] and by [protein|64C6D783FF3F41C81B216F798A1DC8071345B1ED|PNPase] [PubMed|20418391]
  • the [SW|RNA switch] RNA is degraded by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [pubmed|29794222]