Tue May 03 2016 10:04:28 GMT+0200 (CEST)2025-05-27 20:52:25
locus
BSU23150
BSU_23150
ec
outlinks
bsu
BSU23150
BSU_23150
[SW|Categories] containing this gene/protein
[SW|respiration]
Gene
Coordinates on the chromosome (coding sequence)
2,420,804 -> 2,421,343
Gene
Phenotypes of a mutant
essential according to [http://www.ncbi.nlm.nih.gov/pubmed/12682299 Kobayashi et al.], but inactivation of ''resA'' was reported by [http://www.ncbi.nlm.nih.gov/pubmed/12637552 Erlendsson et al.] and by [http://www.ncbi.nlm.nih.gov/pubmed/26735940 Meeske et al. ]
inactivation of ''[SW|resA]'' reduces sporulation efficiency to 45.6% that of wild type cells; delayed entry into sporulation [Pubmed|26735940]
essential according to [http://www.ncbi.nlm.nih.gov/pubmed/12682299 Kobayashi et al.], but inactivation of ''resA'' was reported by [http://www.ncbi.nlm.nih.gov/pubmed/12637552 Erlendsson et al.] and by [http://www.ncbi.nlm.nih.gov/pubmed/26735940 Meeske et al. ]
inactivation of ''[[gene|resA]]'' reduces sporulation efficiency to 45.6% that of wild type cells; delayed entry into sporulation [Pubmed|26735940]
The protein
Protein family
ResA subfamily (according to Swiss-Prot)
[SW|Thioredoxin family] (according to UniProt)
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|8631715]
Expression and Regulation
Regulation
expressed under anaerobic conditions ([[protein|ResD]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8631715,11222591 PubMed]
expressed under conditions of phosphate limitation ([[protein|PhoP]]) [Pubmed|9988472]
repressed by glucose ([[protein|CcpA]]) [Pubmed|16825793]
Expression and Regulation
Regulatory mechanism
[[protein|ResD]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8631715,11222591 PubMed]
[[protein|PhoP]]: transcription activation [Pubmed|9988472]
[[protein|CcpA]]: transcription repression [Pubmed|16825793]
proteinLength
179
geneLength
540
Gene
Coordinates
2,420,804 → 2,421,343
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|Thioredoxin domain] (aa 36-174) (according to UniProt)
The protein
[SW|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE23150 (Δ[[gene|resA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE23150 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTCCACTGCCCCCTTC, downstream forward: _UP4_ATAAAACCCGGAGAGACTTC
BKK23150 (Δ[[gene|resA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK23150 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTCCACTGCCCCCTTC, downstream forward: _UP4_ATAAAACCCGGAGAGACTTC