2017-8-11 16:0:32025-05-22 17:02:51
description
similar to multidrug resistance protein
c-di-AMP exporter
locus
BSU09010
BSU_09010
geneLength
1596
1599
function
unknown
secretion of cyclic di-AMP
product
unknown
c-di-AMP exporter
ec
outlinks
bsu
BSU09010
BSU_09010
Gene
Coordinates
977,775 → 979,373
977,775 979,373
The protein
Protein family
EmrB family (according to Swiss-Prot)
[SW|major facilitator superfamily] (according to UniProt)
[SW|EmrB family] (according to UniProt)
The protein
Paralogous protein(s)
[[protein|LmrB]], [[protein|YcnB]]
[[this]]
The protein
[SW|Localization]
cell membrane (according to Swiss-Prot)
cell membrane (according to UniProt)
Biological materials
Mutant
MGNA-B471 (yhcA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1470 NBRP B. subtilis, Japan]
GP1704 (''[[gene|yhcA]]''::''ermC'', without terminator), available in [SW|Jörg Stülke]'s lab
MGNA-B471 (yhcA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1470 NBRP B. subtilis, Japan]
GP1704 (''[[gene|yhcA]]''::''ermC'', without terminator), available in [SW|Jörg Stülke]'s lab
BKE09010 ([[gene|yhcA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE09010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTAAGACAACCTCCTTT, downstream forward: _UP4_TAATCTGTACAGGGAGGTTT
BKK09010 ([[gene|yhcA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK09010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTAAGACAACCTCCTTT, downstream forward: _UP4_TAATCTGTACAGGGAGGTTT
References
The protein
Catalyzed reaction/ biological activity
secretion of cyclic di-AMP [pubmed|29588402]
The protein
Structure
[PDB|6E8J] (from Hyphomonas neptunium, corresponds to aa 93 ... 204, 28% identity)