SubtiBank SubtiBank
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Tue Dec 13 2016 11:16:32 GMT+0100 (CET)2025-05-24 15:48:34

description

thiamine ABC transporter (binding protein)

thiamine [SW|ECF transporter] (binding protein)

locus

BSU13240

BSU_13240

product

thiamine ABC transporter (binding protein)

thiamine [SW|ECF transporter] (binding protein)

ec

outlinks

bsu

BSU13240

BSU_13240

aminos

MEHICGTSRIAGFRFSLYPMTDDFISVIKSALKKTDTSKVWTKTDHISTVLRGSIDHVFDAAKAIYLHAANSEQHIVMNGTFSIGCPGDTQGDTYLSKGDKRVNEDAVRGLKAEAPCQFALYPMNEPDYMGLIMEAVDIAKAQGTFVQGVHYASELDGDAHDVFSTLEAVFRMAEQQTNHITMTVNLSANSPSRKNRKQG

[SW|Categories] containing this gene/protein

[SW|ABC transporters], [SW|biosynthesis of cofactors], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence)

1,391,040 -> 1,391,642

The protein

[SW|Interactions]

[[protein|ThiW]]-([[protein|ThiV]]-[[protein|ThiX]])-[[protein|ThiU]] [Pubmed|16291685]

Expression and Regulation

Operon

''[[protein|thiU]]-[[protein|thiV]]-[[protein|thiW]]-[[protein|thiX]]'' [Pubmed|16291685]

Expression and Regulation

Regulation

repressed by thiamine ([[protein|Thi-box]]) [Pubmed|12376536]

Expression and Regulation

Regulatory mechanism

[[protein|Thi-box]]: [SW|RNA switch] [Pubmed|12376536]

proteinLength

200

geneLength

603

Gene

Coordinates

1,391,040 1,391,642

The protein

Paralogous protein(s)

[[this]]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-A757 (ykoF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/757 NBRP B. subtilis, Japan]

BKK13240 ([[gene|thiU]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK13240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTCCGACCTCCTGTT, downstream forward: _UP4_AGAAAAAACAGAAAGCAGGG