SubtiBank SubtiBank
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Thu Feb 09 2017 13:44:08 GMT+0100 (CET)2025-05-27 19:39:44

title

yodM

pgpB

description

minor undecaprenyl pyrophosphate phosphatase, not active under standard conditions

phosphatidylglycerol phosphate (PGP) phosphatase , has minor undecaprenyl pyrophosphate phosphatase activity

locus

BSU19650

BSU_19650

function

unknown

phospholipid biosynthesis

product

minor undecaprenyl pyrophosphate phosphatase

phosphatidylglycerol phosphate (PGP) phosphatase

ec

outlinks

bsu

BSU19650

BSU_19650

[SW|Categories] containing this gene/protein

[SW|cell wall synthesis]

Gene

Coordinates on the chromosome (coding sequence)

2,136,913 -> 2,137,524

Biological materials

Mutant

MGNA-B441 (yodM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1440 NBRP B. subtilis, Japan]

GP3652 Δ[[gene|pgpB]]::cat, available in [SW|Jörg Stülke]'s lab

MGNA-B441 (pgpB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1440 NBRP B. subtilis, Japan]

BKE19650 ([[gene|pgpB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE19650 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTTTAACCACCTCAATT, downstream forward: _UP4_TAGAGAGAGGAAAACACAGC

BKK19650 ([[gene|pgpB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK19650 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTTTAACCACCTCAATT, downstream forward: _UP4_TAGAGAGAGGAAAACACAGC

References

27528508, 28168443

27528508, 28168443, 26883633

proteinLength

203

geneLength

612

Gene

Coordinates

2,136,913 2,137,524

The protein

Catalyzed reaction/ biological activity

1,2-diacyl-sn-glycero-3-phospho-(1ʼ-sn-glycero-3ʼ-phosphate) + H2O --> 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate (according to UniProt)

The protein

Protein family

PA-phosphatase related phosphoesterase family (single member, according to UniProt)

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Localization]

cell membrane (integral) [Pubmed|28168443]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Expression and Regulation

additional information

the mRNA is cleaved by [[protein|Rnc|RNase III]] [PubMed|26883633]

Biological materials

Expression vector

pGP3502: IPTG inducible expression, purification in ''E. coli'' with N-terminal His-tag, in [https://www.thermofisher.com/order/catalog/product/K30001#/K30001 pETSUMOadapt], available in [SW|Jörg Stülke]'s lab

pGP3503: IPTG inducible expression, purification in ''E. coli'' with N-terminal Strep-tag, in [SW|pGP172], available in [SW|Jörg Stülke]'s lab

pGP3506 (N-terminal His-tag, expression in ''E. coli'', in [SW|pWH844]), available in [SW|Jörg Stülke]'s lab