comQ [2017-03-21 16:18:21]

prenylation of comX and surfactin expression (srfA)

locus: BSU31710

pI: 4.00

mw: 34.00 kDa

protein length: 299 aa

gene length: 897 bp

function: regulation of quorum sensing

product: prenyltransferase

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.8|Protein modification/ other]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing]
• [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|PhoP regulon]

Gene

Coordinates: 3,256,008 -> 3,256,907

Phenotypes of a mutant

• the mutation suppresses the mucoid phenotype of ''[gene|86C729C7D5ABEE519ADC4A893940600BBB655EF1|motA]'' or ''[gene|FE56753D061344B0F10A6523F49C5C7356AA40B6|motB]'' mutants due to loss of [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|DegU] phosphorylation and concomitant reduced expression of the ''[gene|86C05126ADBA22BB1771B1FA3D214B2E7A36311E|capB]-[gene|D66994D077D1382B88FF65075E44C2A31089548F|capC]-[gene|A696434A086A428D411CAF45B37CD8F82AC2503F|capA]-[gene|6B61DCE8D27776EBF942621D3AE90F410FD13F37|capE]'' operon [Pubmed|24296669]

The protein

Catalyzed reaction/ biological activity

• prenylation of [protein|60D6EB02923D9ADE88F61A8CBBD882BA8BDD457E|ComX] [Pubmed|22878193]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation: [[this]]

References

• 12067344,25666134,19605685,22878193,11133937,1715859,19114482,24296669,24425772,24788106,25036949,25757097,26787913